COVID-19 alert: Travel requirements are changing rapidly, including need for pre-travel COVID-19 testing and quarantine on arrival.

Cheap Holidays to Cayo Santa Maria

Choose two or more items and save on your trip:

Your next trip to Cayo Santa Maria with ebookers

  • Browse our 2021 holiday package deals today! They feature hotels and flights or cars at discounted bundled rates. Book your perfect trip all in one place!
  • You're in luck! We have amazing deals on wonderful properties in Cayo Santa Maria. Start browsing our accommodations simply by using the wizard above.
  • We offer free cancellation on most hotels in case you need to change your plans*

For more information, visit our COVID-19 information page
Find the trip that is just right for you now!

*Some hotels require you to cancel at least 24-48 hours before check-in. Details on site.

Top deals for trips to Cayo Santa Maria

Pod Times Square
Chelsea Savoy Hotel
Hotel 31
The Hotel @ Fifth Avenue
Hotel Mela Times Square

Cayo Santa Maria Holiday Packages for 3 Nights

Pod Times Square
Stewart Hotel
Bentley Hotel
Chelsea Savoy Hotel

Cayo Santa Maria Holiday Packages for 4 Nights

Hotel 31
Americana Inn
Hotel Newton
Hotel Mela Times Square

Cayo Santa Maria Holiday Packages for 5 Nights

Villa Agrippina Gran Meliá - The Leading Hotels of the World
The Palazzo at The Venetian

Cayo Santa Maria Holiday Packages for 6-7 Nights

The Palazzo at The Venetian
The Venetian Resort Las Vegas
Trump International Hotel & Tower New York
NH Collection New York Madison Avenue
Tradewinds Hotel LAX Airport

Best Cayo Santa Maria hotel deals for your holiday

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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

^Savings based on all package bookings with Flight + Hotel made on from as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.