Find Cheap Flights from Santiago (SCL) to Guayaquil (GYE) from

Many airlines offer flexible change policies

Earn BONUS+ rewards on top of your airline points

Enjoy exclusive promotions on the ebookers app!

Cheap Flights from Santiago to Guayaquil & Flight Information
Origin airport IATA code
SCL
Destination airport IATA code
GYE
Number of flight options
1
Average flight time
5 hours 19 mins

Guayaquil GYE Flight Information

Traveling From
Santiago
Origin Airport IATA Code
SCL
Traveling To
Guayaquil
Destination Airport IATA Code
GYE
Number of Airlines Serving
1
Available Airlines
Distance
3601 km
Direct Flight Time
1 19
Flight Price

Frequently asked questions

Is there a direct flight between Santiago and Guayaquil?
A direct flight between Nuevo Pudahuel Airport and Jose Joaquin de Olmedo Intl. Airport (GYE) means extra time for thrills and adventure at the other end. You’ll find 1 air carriers flying this route nonstop, including LATAM Airlines, which is one of the most popular.
How long is a direct flight from Santiago to Guayaquil?
It takes roughly 5 hours and 23 minutes, but times can vary depending on type of plane used, wind and any delays. The total travel distance from Santiago to Guayaquil is 2,200 miles.
What are the best airports for Santiago to Guayaquil flights?
SCL is probably where you’ll be leaving from if you’re travelling from Santiago to Guayaquil. Like to know where you’ll be disembarking? The odds are it’ll be Guayaquil (GYE-Jose Joaquin de Olmedo Intl.).
What are some of the most popular airlines flying from Santiago to Guayaquil?
If you plan to travel from Santiago to Guayaquil and want terrific service and good in-flight entertainment, one of these leading air carriers might just be what you’re after.

  • Copa Airlines with 91 flights every month.
  • Avianca with 30 flights every month.
  • American Airlines with 30 flights every month.
  • LATAM Airlines with 30 flights every month.

How many flights are there from Santiago to Guayaquil?
You’ve got plenty of choice when it comes to travelling from Santiago to Guayaquil. With 6 flights operating each day, the time to escape is up to you.
What are the cheapest days to book a flight?
This is one is easy to remember: Ticket Thursdays. We found that tickets booked on a Thursday resulted in the best deal on average in 2021. However, Friday can be the worst day to purchase plane tickets, as it was the day with the highest average ticket price based on flight demand on ebookers in 2021.
What are the cheapest days to fly?
When analysing flight demand on ebookers in 2021, Friday turned out to be the cheapest day to fly, with Tuesday as a close second. That’s definitely something to consider when booking your next trip! Thinking of traveling mid-week? It turns out that Wednesdays generally had the most expensive airline tickets, so keep this in mind when planning for your next trip.*According to flight demand on ebookers.com from January to December 2021. Savings are subject to change and may vary depending on selections made.

Fly from Santiago to Guayaquil with ebookers

Cheap flights from Santiago to Guayaquil 

Our advanced search tools and comprehensive filters help you find a flight that fits your budget. To search for cheap flights, just enter your travel dates and sort your results by price. With all available tickets listed lowest price first, it’s easy to select the one that’s easiest on your wallet.  

To find the cheapest flights from Santiago to Guayaquil, you can also travel outside peak season. The more flexible you can be on travel dates, the easier it is to find those cheap flight tickets. We know, for example, that the cheapest time to travel between Santiago to Guayaquil is . In the current list of deals available, prices start at and can rise to for return flights.  

Find the best flight from Santiago to Guayaquil  

Every day between Santiago and Guayaquil, 1 flights from 1 airlines jet back and forth. And with ebookers, you can book tickets for any one of those flights. If you book a direct flight with LATAM Airlines, you’ll arrive safely in your destination in around 1hours. If you can think of a quicker way to cover the 3601 km between null and null, let us know! 

Flights from Santiago to Guayaquil — a great choice on great deals 

We only need a little information to give you a lot of choice. Just tell us when you’re planning your family holiday, long weekend, luxury getaway or quick business trip, and we’ll do the rest. And to keep your choice-making easy, we’ve given you plenty of ways to narrow down your search. Choose one-way, roundtrip or multi city flights, select your preferred airline, your time of arrival and departure and cabin class using the filters.  

Once you’ve told us what you want, we’ll show you what’s on offer. All you need to do is take your pick and start packing.  

Book your flights with ebookers 

We want the experience of booking your flight from Santiago to Guayaquil to be as simple as possible. That’s why we designed our search and filter options to make your life easy. Whether you are travelling on business or for pleasure, ebookers has you covered. 

When you’re ready to book, our service is always fast and transparent. We know plans change, so we have a range of flexible booking options. Choose between refundable bookings and flights with no charges should you need to rearrange and travel stress-free. 

Need a car after flight from Santiago to Guayaquil

Place to stay after flight from Santiago to Guayaquil

Wyndham Guayaquil Puerto Santa Ana

Wyndham Guayaquil Puerto Santa Ana

4.5 out of 5
Calle Numa Pompilio Llona S N, Ciudad del Rio - Puerto Santa Ana, Guayaquil, Guayas
Stay at this 4.5-star luxury hotel in Guayaquil. Enjoy free WiFi, free parking and 2 restaurants. Our guests praise the helpful staff and the clean rooms in ...
9/10 Wonderful! (1,000 reviews)
"Ubicación"

Reviewed on 19 Mar 2024

Wyndham Guayaquil Puerto Santa Ana
Wyndham Garden Guayaquil

Wyndham Garden Guayaquil

3.5 out of 5
Juan Tanca Marengo Ave, Abel Romero St. Plaza Del Sol, Guayaquil, Guayas
Stay at this 3.5-star business-friendly hotel in Guayaquil. Enjoy free breakfast, free WiFi and 2 restaurants. Our guests praise the breakfast and the helpful ...
8.6/10 Excellent! (1,006 reviews)
"Thank you for the good job!!!"

Reviewed on 21 Mar 2024

Wyndham Garden Guayaquil
Holiday Inn Guayaquil Airport, an IHG Hotel

Holiday Inn Guayaquil Airport, an IHG Hotel

3.5 out of 5
Av. de Las Américas,junto al Aeropuerto, Intl. Jose Joaquin de Olmedo, Guayaquil, Guayas
Stay at this 3.5-star business-friendly hotel in Guayaquil. Enjoy free WiFi, free parking and breakfast. Our guests praise the breakfast and the restaurant in ...
9/10 Wonderful! (1,006 reviews)
"Amazing I will definitely come back"

Reviewed on 23 Mar 2024

Holiday Inn Guayaquil Airport, an IHG Hotel
Save an average of 15% on thousands of hotels when you're signed in
TRYP by Wyndham Guayaquil Airport

TRYP by Wyndham Guayaquil Airport

4.5 out of 5
Av. Joaquín Orrantia y L. Benitez, Guayaquil, Guayas
Stay at this 4.5-star luxury hotel in Guayaquil. Enjoy free WiFi, free valet parking and breakfast. Our guests praise the breakfast and the helpful staff in ...
8.6/10 Excellent! (909 reviews)
"very nice staff always a pleasure to stay here"

Reviewed on 25 Mar 2024

TRYP by Wyndham Guayaquil Airport
Oro Verde Guayaquil

Oro Verde Guayaquil

5 out of 5
9 De Octubre Y Garcia Moreno, Guayaquil, Guayas
Stay at this spa hotel in Guayaquil. Enjoy free WiFi, free parking and 5 restaurants. Our guests praise the breakfast and the helpful staff in their reviews. ...
9.4/10 Exceptional! (1,005 reviews)
"The pool was nice and clean. The sauna was clean the food excellent buffet."

Reviewed on 26 Mar 2024

Oro Verde Guayaquil
Hilton Colon Guayaquil

Hilton Colon Guayaquil

4.5 out of 5
Av Francisco de Orellana Mz 111, Guayaquil
Stay at this luxury hotel in Guayaquil. Enjoy free WiFi, free parking and 5 restaurants. Our guests praise the pool and the helpful staff in their reviews. Popular ...
8.4/10 Very Good! (563 reviews)
"Excellent"

Reviewed on 22 Mar 2024

Hilton Colon Guayaquil
Don't see what you're looking for?
See all available properties in Guayaquil
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

*Savings based on all holiday package bookings with Flight + Hotel on ebookers.com from January 2017 to December 2017, as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages. For Free Flight or 100% Off Flight deals, package savings is greater than or equal to the current cost of one component, when both are priced separately.

Fare, taxes & fees: Fares were found on ebookers.com and are updated daily. They include all taxes and fees, except baggage fees.

Refunds/changes/cancellations: Itinerary changes, if permitted for the fare, will have a £25.00 / 45.00 Euro service fee charged by ebookers, plus any airline fare and tax increase that may be applicable.

Other conditions: Schedules, fares and rules are subject to change without notice. Seats are limited and may not be available on all flights/dates or in all markets. Fares will not be honored retroactively or in exchange for any wholly/partially unused ticket. Tickets are non-transferable and non-refundable. Fare rules are provided for the selected itinerary before booking.